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Tucatinib Oral Tablet (TUCATINIB - ORAL)

For treating cancer.

Brand Name(s): Tukysa

Generic Name: Tucatinib

Instructions

Swallow the medicine without crushing or chewing it.

This medicine may be taken with or without food.

This medicine is usually combined with another medicine to treat your condition.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Keep the desiccant (drying) packet in the bottle and keep the bottle closed tightly.

Discard any unused medicine after 3 months.

If you vomit after taking a dose, do not take an extra dose. Take your next dose at the usual time.

If you forget a dose, just wait. Use the next dose at the usual time. Do not use 2 doses at once.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

To avoid a serious skin reaction, avoid heat and hot water. Also avoid pressure on elbows, knees, and feet. For example, avoid tight clothing, kneeling, or long walks.

Do not use the medication any more than instructed.

Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women must use reliable forms of birth control while taking this medicine and for 1 week after stopping to prevent pregnancy.

Men with a female partner who is of childbearing age must use reliable birth control during sexual activity while taking this medicine and for 1 week after stopping to prevent pregnancy.

Do not take St. John's wort while on this medicine.

Women who are pregnant or in their childbearing years should not touch or handle this medicine. This medicine can be absorbed through the woman's skin and harm the unborn baby.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • decreased appetite
  • diarrhea
  • lack of energy and tiredness
  • mouth sores or irritation
  • joint or muscle pain
  • nausea and vomiting
  • weight loss

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe, watery or bloody diarrhea
  • dizziness
  • dry mouth
  • pain, redness, swelling or blistering on hands, feet or elbows
  • sores or blisters on hands or feet
  • fast or irregular heart beats
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.